Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors

@article{Poeschla1998EfficientTO,
  title={Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors},
  author={Eric M. Poeschla and Flossie Wong-Staal and David J. Looney},
  journal={Nature Medicine},
  year={1998},
  volume={4},
  pages={354-357}
}
The molecular bases for species barriers to lentiviral replication are not well understood, but are of interest for explaining lentiviral pathogenesis, devising therapeutic strategies, and adapting lentiviruses to gene therapy. HIV-1 -based lentiviral vectors efficiently transduce nondividing cells1, but present complex safety concerns2. Nonprimate (ungulate or feline) lentiviruses might provide safer alternatives, but these viruses display highly restricted tropisms, and their potential for… 
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TLDR
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TLDR
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