Efficient sorting of genomic permutations by translocation, inversion and block interchange

@article{Yancopoulos2005EfficientSO,
  title={Efficient sorting of genomic permutations by translocation, inversion and block interchange},
  author={Sophia Yancopoulos and Oliver Attie and Richard Friedberg},
  journal={Bioinformatics},
  year={2005},
  volume={21 16},
  pages={
          3340-6
        }
}
MOTIVATION Finding genomic distance based on gene order is a classic problem in genome rearrangements. Efficient exact algorithms for genomic distances based on inversions and/or translocations have been found but are complicated by special cases, rare in simulations and empirical data. We seek a universal operation underlying a more inclusive set of evolutionary operations and yielding a tractable genomic distance with simple mathematical form. RESULTS We study a universal double-cut-and… 

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