Efficient receptor-independent intracellular translocation of aptamers mediated by conjugation to carbon nanotubes.

@article{Bossche2010EfficientRI,
  title={Efficient receptor-independent intracellular translocation of aptamers mediated by conjugation to carbon nanotubes.},
  author={Jeroen Van den Bossche and Wafa' T. Al-Jamal and Bowen Tian and Antonio Nunes and Chiara del Fabbro and Alberto Bianco and Maurizio Prato and Kostas Kostarelos},
  journal={Chemical communications},
  year={2010},
  volume={46 39},
  pages={
          7379-81
        }
}
We have covalently grafted aptamers onto carboxylated carbon nanotubes to design a novel vector system that can easily translocate into the cytosol of different cell types independent of receptor-mediated uptake. We propose the use of carbon nanotubes for the efficient intracellular delivery of biologically active aptamers for potential therapeutic applications. 

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