Efficient production of nanobodies against urease activity ofHelicobacter pylori in Pichia pastoris.

Abstract

BACKGROUND/AIM Helicobacter pylori is a major health problem. One of the therapeutic approaches is administration of antibody against H. pylori. The methylotrophic Pichia pastoris is a suitable host for expression of recombinant antibody fragments. The aims of this study were the expression and the evaluation of camelid nanobody in the yeast Pichia pastoris… (More)
DOI: 10.3906/sag-1509-121

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