Efficient parameter estimation for spatio-temporal models of pattern formation: case study of Drosophila melanogaster

@article{FomekongNanfack2007EfficientPE,
  title={Efficient parameter estimation for spatio-temporal models of pattern formation: case study of Drosophila melanogaster},
  author={Yves Fomekong-Nanfack and Jaap A. Kaandorp and Joke G. Blom},
  journal={Bioinformatics},
  year={2007},
  volume={23 24},
  pages={3356-63}
}
MOTIVATION Diffusable and non-diffusable gene products play a major role in body plan formation. A quantitative understanding of the spatio-temporal patterns formed in body plan formation, by using simulation models is an important addition to experimental observation. The inverse modelling approach consists of describing the body plan formation by a rule-based model, and fitting the model parameters to real observed data. In body plan formation, the data are usually obtained from fluorescent… CONTINUE READING

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