Efficient nanocarriers of siRNA therapeutics for cancer treatment.

  title={Efficient nanocarriers of siRNA therapeutics for cancer treatment.},
  author={Md Abdus Subhan and Vladimir Torchilin},
  journal={Translational research : the journal of laboratory and clinical medicine},
Nanocarriers as drug delivery systems are promising and becoming popular, especially for cancer treatment. In addition to improving the pharmacokinetics of poorly soluble hydrophobic drugs by solubilizing them in a hydrophobic core, nanocarriers allow cancer-specific combination drug deliveries by inherent passive targeting phenomena and adoption of active targeting strategies. Nanoparticle-drug formulations can enhance the safety, pharmacokinetic profiles, and bioavailability of locally or… CONTINUE READING