Efficient multicomponent reaction synthesis of the schistosomiasis drug praziquantel.


Schistosomiasis, also known as snail fever, is a very large but nevertheless neglected tropical disease (NTD) affecting more than 200 million people worldwide, with more than 90% occurring in sub-Saharan Africa. More than 700 million people live in areas where schistosomiasis is endemic. The causing disease agents are the small worms S. haematobium and… (More)
DOI: 10.1002/chem.201002046


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