Efficient inducation of local and systemic antitumor immune response by liposome-mediated intratumoral co-transfer of interleukin-2 gene and interleukin-6 gene.

@article{Cao1999EfficientIO,
  title={Efficient inducation of local and systemic antitumor immune response by liposome-mediated intratumoral co-transfer of interleukin-2 gene and interleukin-6 gene.},
  author={Xiao-wei Cao and Quan-xing Wang and Dian Wen Ju and Qun Tao and Jing Wang},
  journal={Journal of experimental & clinical cancer research : CR},
  year={1999},
  volume={18 2},
  pages={191-200}
}
Interleukin 2 (IL-2) expressing plasmid and interleukin 6 (IL-6)-expressing plasmid were encapsulated in liposome and administrated intratumoraly into tumor-bearing mice 4 days after subcutaneous inoculation of B16F10 melanoma cells. The results showed that treatment of tumor-bearing mice with IL-2 gene or IL-6 gene transfer inhibited the growth of… CONTINUE READING