Efficient gene editing in Corynebacterium glutamicum using the CRISPR/Cas9 system

@inproceedings{Peng2017EfficientGE,
  title={Efficient gene editing in Corynebacterium glutamicum using the CRISPR/Cas9 system},
  author={Feng Peng and Xinyue Wang and Yang Sun and Guibin Dong and Yankun Yang and Xiuxia Liu and Zhonghu Bai},
  booktitle={Microbial cell factories},
  year={2017}
}
BACKGROUND Corynebacterium glutamicum (C. glutamicum) has traditionally been used as a microbial cell factory for the industrial production of many amino acids and other industrially important commodities. C. glutamicum has recently been established as a host for recombinant protein expression; however, some intrinsic disadvantages could be improved by genetic modification. Gene editing techniques, such as deletion, insertion, or replacement, are important tools for modifying chromosomes… CONTINUE READING
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