Efficient expression of gene variants that harbour AGA codons next to the initiation codon

@inproceedings{ZamoraRomo2007EfficientEO,
  title={Efficient expression of gene variants that harbour AGA codons next to the initiation codon},
  author={Efra{\'i}n Zamora-Romo and Luis Rogelio Cruz-Vera and Seraf{\'i}n Vivanco-Dom{\'i}nguez and Marco Antonio Magos-Castro and Gabriel Guarneros},
  booktitle={Nucleic acids research},
  year={2007}
}
In an effort to improve the knowledge about the rules which direct the effect of the early ORF sequences on translation efficiency, we have analyzed the effect of pairs of the six arginine codons at the second and third positions on the expression of lacZ variants. Whereas the pairs of identical AGA or AGG codons were favorable for the gene expression, identical pairs of each of the four CGN codons were very inefficient. This result was unexpected because tandems of AGA or AGG codons located in… CONTINUE READING

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