Efficient differentiation of human embryonic stem cells into functional cerebellar-like cells.

Abstract

The cerebellum has critical roles in motor and sensory learning and motor coordination. Many cerebellum-related disorders indicate cell therapy as a possible treatment of neural loss. Here we show that application of inductive signals involved in early patterning of the cerebellar region followed by application of different factors directs human embryonic… (More)
DOI: 10.1089/scd.2009.0498

Topics

Cite this paper

@article{Erceg2010EfficientDO, title={Efficient differentiation of human embryonic stem cells into functional cerebellar-like cells.}, author={Slaven Erceg and Mohammad Ronaghi and Ivan Zipancic and Sergio La{\'i}nez and Mireia G{\'a}rcia Rosell{\'o} and Chen Xiong and Victoria Moreno-Manzano and Fernando Javier Rodr{\'i}guez-Jim{\'e}nez and Rosa Planells and Manuel Alvarez-Dolado and Shom Shanker Bhattacharya and Miodrag Stojkovi{\'c}}, journal={Stem cells and development}, year={2010}, volume={19 11}, pages={1745-56} }