Efficient derivation of functional hepatocytes from mouse induced pluripotent stem cells by a combination of cytokines and sodium butyrate.

@article{Zhang2011EfficientDO,
  title={Efficient derivation of functional hepatocytes from mouse induced pluripotent stem cells by a combination of cytokines and sodium butyrate.},
  author={Qi Zhang and Yang Yang and Jian Zhang and Guoying Wang and Wei Liu and Dong-Bo Qiu and Ziqing Hei and Qi-Long Ying and Guihua Chen},
  journal={Chinese medical journal},
  year={2011},
  volume={124 22},
  pages={3786-93}
}
BACKGROUND Hepatocyte transplantation has been proposed as an alternative to whole-organ transplantation to support many forms of hepatic insufficiency. Unfortunately, the lack of donor livers makes it difficult to obtain enough viable human hepatocytes for hepatocyte-based therapies. Therefore, it is urgent to find new ways to provide ample hepatocytes… CONTINUE READING