Efficient derivation of bovine embryonic stem cells needs more than active core pluripotency factors.


Pluripotency can be captured in vitro, providing that the culture environment meets the requirements that avoid differentiation while stimulating self-renewal. From studies in the mouse embryo, two kinds of pluripotent stem cells have been obtained from the early and late epiblast, embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs), representing… (More)
DOI: 10.1002/mrd.22051