Efficient de novo synthesis of resveratrol by metabolically engineered Escherichia coli

@article{Wu2017EfficientDN,
  title={Efficient de novo synthesis of resveratrol by metabolically engineered Escherichia coli},
  author={Junjun Wu and Peng Zhou and Xia Zhang and Mingsheng Dong},
  journal={Journal of Industrial Microbiology & Biotechnology},
  year={2017},
  volume={44},
  pages={1083-1095}
}
Resveratrol has been the subject of numerous scientific investigations due to its health-promoting activities against a variety of diseases. However, developing feasible and efficient microbial processes remains challenging owing to the requirement of supplementing expensive phenylpropanoic precursors. Here, various metabolic engineering strategies were developed for efficient de novo biosynthesis of resveratrol. A recombinant malonate assimilation pathway from Rhizobium trifolii was introduced… CONTINUE READING
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