Efficient cultivation of neural stem cells with controlled delivery of FGF-2.

@article{Galderisi2013EfficientCO,
  title={Efficient cultivation of neural stem cells with controlled delivery of FGF-2.},
  author={Umberto Galderisi and Gianfranco Peluso and Gianni Di Bernardo and Anna Calarco and Mariella D'Apolito and Orsolina Petillo and Marilena Cipollaro and Francesca R Fusco and Mariarosa Anna Beatrice Melone},
  journal={Stem cell research},
  year={2013},
  volume={10 1},
  pages={
          85-94
        }
}
Neural stem cells (NSCs) raised the hope for cell-based therapies in human neurodevelopmental and neurodegenerative diseases. Current research strategies aim to isolate, enrich, and propagate homogeneous populations of neural stem cells. Unfortunately, several concerns with NSC cultures currently may limit their therapeutic promise. Exhaustion of growth factors and/or their uncontrolled release with burst and fall in their concentration may greatly affect the in vitro behavior of NSCs. In this… CONTINUE READING
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