Efficient and reproducible generation of tumour-infiltrating lymphocytes for renal cell carcinoma

@inproceedings{Baldan2015EfficientAR,
  title={Efficient and reproducible generation of tumour-infiltrating lymphocytes for renal cell carcinoma},
  author={Vania Baldan and Richard Griffiths and Robert Edward Hawkins and David Edward Gilham},
  booktitle={British Journal of Cancer},
  year={2015}
}
Background:Tumour-infiltrating lymphocyte (TIL) therapy is showing great promise in the treatment of patients with advanced malignant melanoma. However, the translation of TIL therapy to non-melanoma tumours such as renal cell carcinoma has been less successful with a major constraint being the inability to reproducibly generate TILs from primary and metastatic tumour tissue.Methods:Primary and metastatic renal cell carcinoma biopsies were subjected to differential tumour disaggregation methods… CONTINUE READING
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