Efficient and cost-effective extraction of genomic DNA from formalin-fixed and paraffin-embedded tissues.

@article{Weiss2011EfficientAC,
  title={Efficient and cost-effective extraction of genomic DNA from formalin-fixed and paraffin-embedded tissues.},
  author={Alexander Th A Weiss and N M Delcour and Anne S. Meyer and Robert Klopfleisch},
  journal={Veterinary pathology},
  year={2011},
  volume={48 4},
  pages={834-8}
}
Diagnostic and investigative molecular pathology frequently has to resort to extraction of DNA from formalin-fixed and paraffin-embedded tissue samples. Although many different protocols are reported for this type of material, extraction of sufficient amounts of intact DNA is still challenging. Here, the authors report a reproducible, simple, cost-effective, and efficient protocol that yields up to 140 μg of DNA from approximately 10 to 15 mg of formalin-fixed and paraffin-embedded tissue… CONTINUE READING