Efficient Transposition of the piggyBac (PB) Transposon in Mammalian Cells and Mice

@article{Ding2005EfficientTO,
  title={Efficient Transposition of the piggyBac (PB) Transposon in Mammalian Cells and Mice},
  author={Sheng Ding and Xiaohui Wu and Gang Li and Min Han and Yuan Zhuang and Tian Xu},
  journal={Cell},
  year={2005},
  volume={122},
  pages={473-483}
}
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Transposable elements have been routinely used for genetic manipulation in lower organisms, including generating transgenic animals and insertional mutagenesis. [...] Key Result We show that PB elements carrying multiple genes can efficiently transpose in human and mouse cell lines and also in mice. PB permits the expression of the marker genes it carried.Expand Abstract

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