Efficient Synthesis of Epoxides from Vicinal Diols Via Cyclic Sulfates

@article{Jang2000EfficientSO,
  title={Efficient Synthesis of Epoxides from Vicinal Diols Via Cyclic Sulfates},
  author={D. O. Jang and Y. Joo and D. H. Cho},
  journal={Synthetic Communications},
  year={2000},
  volume={30},
  pages={4489 - 4494}
}
  • D. O. Jang, Y. Joo, D. H. Cho
  • Published 2000
  • Chemistry
  • Synthetic Communications
  • Abstract Reaction of cyclic sulfates of vic-diols with sodium hydroxide in THF-MeOH produced the corresponding epoxides in excellent isolated yields at room temperature. Cyclic sulfates of trans-diols gave cis-epoxides, and cyclic sulfates of cis-diols afforded trans-epoxides exclusively. Various cyclic sulfates of vic-diols can be converted into the epoxides under the conditions. 
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    References

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