Efficient Generation of Hypothalamic Neurons from Human Pluripotent Stem Cells.

@article{Wang2016EfficientGO,
  title={Efficient Generation of Hypothalamic Neurons from Human Pluripotent Stem Cells.},
  author={Liheng Wang and Dieter Egli and Rudolph L. Leibel},
  journal={Current protocols in human genetics},
  year={2016},
  volume={90},
  pages={21.5.1-21.5.14}
}
The hypothalamus comprises neuronal clusters that are essential for body weight regulation and other physiological functions. Insights into the complex cellular physiology of this region of the brain are critical to understanding the pathogenesis of obesity, but human hypothalamic cells are largely inaccessible for direct study. Here we describe a technique… CONTINUE READING