Efficient Generation of Functional Dopaminergic Neurons from Human Induced Pluripotent Stem Cells Under Defined Conditions

@inproceedings{Swistowski2010EfficientGO,
  title={Efficient Generation of Functional Dopaminergic Neurons from Human Induced Pluripotent Stem Cells Under Defined Conditions},
  author={Andrzej Swistowski and Jun Peng and Qiuyue Liu and Prashant Mali and Mahendra S. Rao and Linzhao Cheng and Xianmin Zeng},
  booktitle={Stem cells},
  year={2010}
}
Human induced pluripotent stem cells (iPSCs) reprogrammed from somatic cells represent a promising unlimited cell source for generating patient-specific cells for biomedical research and personalized medicine. As a first step, critical to clinical applications, we attempted to develop defined culture conditions to expand and differentiate human iPSCs into functional progeny such as dopaminergic neurons for treating or modeling Parkinson's disease (PD). We used a completely defined (xeno-free… CONTINUE READING
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