Efficient Generation of Dilution Gradients With Digital Microfluidic Biochips

@article{Bhattacharjee2019EfficientGO,
  title={Efficient Generation of Dilution Gradients With Digital Microfluidic Biochips},
  author={Sukanta Bhattacharjee and Ansuman Banerjee and Tsung-Yi Ho and Krishnendu Chakrabarty and Bhargab B. Bhattacharya},
  journal={IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems},
  year={2019},
  volume={38},
  pages={874-887}
}
Digital microfluidic biochips (DMFBs) are now being extensively used to automate several biochemical laboratory protocols such as clinical analysis, point-of-care diagnostics, or DNA sequencing. In many biological assays, e.g., bacterial susceptibility tests and cellular response analysis, samples, or reagents are required in multiple concentration (or dilution) factors, satisfying certain gradient patterns such as linear, exponential, or parabolic. Dilution gradients are traditionally prepared… CONTINUE READING

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