Efficient Differentiation of Human Induced Pluripotent Stem Cell (hiPSC) Derived Hepatocyte-Like Cells on hMSCs Feeder

@inproceedings{Mobarra2014EfficientDO,
  title={Efficient Differentiation of Human Induced Pluripotent Stem Cell (hiPSC) Derived Hepatocyte-Like Cells on hMSCs Feeder},
  author={Naser Mobarra and Masoud Soleimani and Fatemeh Kouhkan and Zahra Hesari and Reyhaneh Lahmy and Majid Mossahebi-Mohammadi and Ehsan Arefian and Zahra Jaafarpour and Hajar Nasiri and Reza Pakzad and Rezvan Tavakoli and Parvin Pasalar},
  booktitle={International journal of hematology-oncology and stem cell research},
  year={2014}
}
BACKGROUND The use of stem cells is considered as an appropriate source in cell therapy and tissue engineering. Differentiation of human induced Pluripotent Stem Cells (hiPSCs) to Hepatocyte-like Cells (HLCs) on mouse embryonic fibroblasts (MEFs) feeders is confronted with several problems that hinder the clinical applications of these differentiated cells for the treatment of liver injuries. Safe appropriate cells for stem cell-based therapies could create new hopes for liver diseases. This… CONTINUE READING
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