Efficient Derivation of Human Neuronal Progenitors and Neurons from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction

@inproceedings{Parsons2011EfficientDO,
  title={Efficient Derivation of Human Neuronal Progenitors and Neurons from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction},
  author={Xuejun Huang Parsons and Yang Dong Teng and James F. Parsons and Evan Y. Snyder and David B. Smotrich and Dennis A. Moore},
  booktitle={Journal of visualized experiments : JoVE},
  year={2011}
}
There is a large unfulfilled need for a clinically-suitable human neuronal cell source for repair or regeneration of the damaged central nervous system (CNS) structure and circuitry in today's healthcare industry. Cell-based therapies hold great promise to restore the lost nerve tissue and function for CNS disorders. However, cell therapies based on CNS-derived neural stem cells have encountered supply restriction and difficulty to use in the clinical setting due to their limited expansion… CONTINUE READING

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