Efficient DNA packaging of bacteriophage PRD1 requires the unique vertex protein P6.

@article{Karhu2007EfficientDP,
  title={Efficient DNA packaging of bacteriophage PRD1 requires the unique vertex protein P6.},
  author={Nelli J Karhu and Gabija Žiedaitė and Dennis Henry Bamford and Jaana K. H. Bamford},
  journal={Journal of virology},
  year={2007},
  volume={81 6},
  pages={2970-9}
}
The assembly of bacteriophage PRD1 proceeds via formation of empty procapsids containing an internal lipid membrane, into which the linear double-stranded DNA genome is subsequently packaged. The packaging ATPase P9 and other putative packaging proteins have been shown to be located at a unique vertex of the PRD1 capsid. Here, we describe the isolation and characterization of a suppressor-sensitive PRD1 mutant deficient in the unique vertex protein P6. Protein P6 was found to be an essential… CONTINUE READING

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