Efficient DNA Packaging of Bacteriophage PRD1 Requires the Unique Vertex Protein P6

@article{Karhu2007EfficientDP,
  title={Efficient DNA Packaging of Bacteriophage PRD1 Requires the Unique Vertex Protein P6},
  author={Nelli J Karhu and Gabija Žiedaitė and Dennis H Bamford and Jaana K H Bamford},
  journal={Journal of Virology},
  year={2007},
  volume={81},
  pages={2970 - 2979}
}
  • Nelli J Karhu, Gabija Žiedaitė, +1 author Jaana K H Bamford
  • Published 2007
  • Medicine, Biology
  • Journal of Virology
  • ABSTRACT The assembly of bacteriophage PRD1 proceeds via formation of empty procapsids containing an internal lipid membrane, into which the linear double-stranded DNA genome is subsequently packaged. The packaging ATPase P9 and other putative packaging proteins have been shown to be located at a unique vertex of the PRD1 capsid. Here, we describe the isolation and characterization of a suppressor-sensitive PRD1 mutant deficient in the unique vertex protein P6. Protein P6 was found to be an… CONTINUE READING

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