Efficiency of the APTIMA HPV Assay for detection of HPV RNA and DNA targets.

@article{Getman2009EfficiencyOT,
  title={Efficiency of the APTIMA HPV Assay for detection of HPV RNA and DNA targets.},
  author={Damon K Getman and Aparna Aiyer and Janel Dockter and Cristina Giachetti and Fan Zhang and Christine C Ginocchio},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2009},
  volume={45 Suppl 1},
  pages={S49-54}
}
BACKGROUND The APTIMA HPV Assay (AHPV) is designed to detect HPV E6/E7 mRNA from 14 high-risk types in Cytyc PreservCyt liquid-based cytology specimens. OBJECTIVES To compare AHPV analytical sensitivity for RNA and DNA; to compare the sensitivity of AHPV and Hybrid Capture 2 (HC2) assays for HPV DNA detection; to compare assay performance with and without sample denaturation; to compare assay results with cytology. STUDY DESIGN Analytical sensitivity of AHPV for detecting E6/E7 RNA was… CONTINUE READING