Efficiency of in vivo gene transfection into transplanted rat heart by coronary infusion of HVJ liposome.

@article{Sawa1995EfficiencyOI,
  title={Efficiency of in vivo gene transfection into transplanted rat heart by coronary infusion of HVJ liposome.},
  author={Yoshiki Sawa and Kazuo Suzuki and H z Bai and Ryota Shirakura and Ryuichi Morishita and Yasufumi Kaneda and H Matsuda},
  journal={Circulation},
  year={1995},
  volume={92 9 Suppl},
  pages={
          II479-82
        }
}
BACKGROUND Current methods of in vivo gene transfer into myocardium are limited by low efficiency. To improve in vivo gene transfer, a gene transfer method using hemagglutinating virus of Japan (HVJ) as a viral vector can be an alternative. METHODS AND RESULTS In vivo gene transfection of FITC-labeled oligonucleotide (F-ODN) and cDNA of beta-galactosidase (beta-gal) was examined with use of the HVJ liposome (H group) or without it (C group). In the H group, F-ODN or cDNA of beta-gal were… CONTINUE READING

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