Efficiency of hydroxychloroquine in the treatment of granulomatous complications in chronic granulomatous disease.

@article{Arlet2008EfficiencyOH,
  title={Efficiency of hydroxychloroquine in the treatment of granulomatous complications in chronic granulomatous disease.},
  author={Jean-Benoit Arlet and Achile Aouba and Felipe Suarez and St{\'e}phane Blanche and Dominique Valeyre and Alain Fischer and Diane Damotte and Christophe Cellier and Olivier Hermine},
  journal={European journal of gastroenterology & hepatology},
  year={2008},
  volume={20 2},
  pages={
          142-4
        }
}
Chronic granulomatous disease (CGD) represents a group of genetic disorders in which impaired intracellular microbial killing by phagocytes leads to recurrent bacterial and fungal infections and granuloma formation. Granulomatous lesions involved gastrointestinal tract in more than one-third of all CGD patients, with various clinical presentations, and may be life threatening. Corticosteroid therapy may relieve symptoms but increase the risk of infections in such immunocompromised patients. We… CONTINUE READING