Efficiency of human monozygotic twins in studies of blood lipids.

@article{Christian1972EfficiencyOH,
  title={Efficiency of human monozygotic twins in studies of blood lipids.},
  author={Joe C. Christian and Ke Won Kang},
  journal={Metabolism: clinical and experimental},
  year={1972},
  volume={21 8},
  pages={691-9}
}
The cost of human experimentation often severely limits the size of experimental groups in studies of human metabolism. In animal studies workers have found that monozygotic (MZ) twins are efficient experimental subjects, because small, within twin-pair differences allow experiments to be done with fewer animals. This communication presents a method of using uniformity trials (all experimental subjects treated alike) to estimate the efficiency of MZ twins relative to unrelated experimental… CONTINUE READING