Efficiency of aerosol medication delivery from a metered dose inhaler versus jet nebulizer in infants with bronchopulmonary dysplasia.

@article{Fok1996EfficiencyOA,
  title={Efficiency of aerosol medication delivery from a metered dose inhaler versus jet nebulizer in infants with bronchopulmonary dysplasia.},
  author={Tai Fai Fok and Shelley L Monkman and Myrna B. Dolovich and Sarah Gray and Geoffrey Coates and Bosco Paes and Farhan Rashid and Mike Newhouse and Haresh H Kirpalani},
  journal={Pediatric pulmonology},
  year={1996},
  volume={21 5},
  pages={301-9}
}
The best means for optimal delivery of drugs into lungs of infants with bronchopulmonary dysplasia (BPD) is uncertain. We aimed to measure radio-aerosol deposition of salbutamol by jet nebulizer and metered dose inhalers (MDI) in ventilated and non-ventilated BPD infants. In a randomized, crossover sequence, salbutamol lung deposition was measured using an MDI (2 puffs or 200 micrograms) or sidestream jet nebulizer (5 minutes of nebulization with 100 micrograms/kg) in 10 ventilated (mean… CONTINUE READING

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