Efficiency of a specific albumin extinguisher locus in monochromosomal hepatoma hybrids.


Fusion of hepatoma cells with cells of similar ploidy (1s) from different histogenetic origin results in the systematic and stable extinction of hepatic traits. However, doubling the ploidy of the hepatoma parent (2s) leads to the formation of hybrids in which extinction is not observed. To establish if these dosage effects reflect, as generally thought… (More)