Efficiency and safety of ondansetron in preventing postanaesthesia shivering.

@article{He2016EfficiencyAS,
  title={Efficiency and safety of ondansetron in preventing postanaesthesia shivering.},
  author={Kun He and H. C. Zhao and H C Zhou},
  journal={Annals of the Royal College of Surgeons of England},
  year={2016},
  volume={98 6},
  pages={
          358-66
        }
}
  • K. He, H. Zhao, H. Zhou
  • Published 3 May 2016
  • Medicine
  • Annals of the Royal College of Surgeons of England
Introduction Shivering is one of the most frequent complications of operation during the postanaesthesia period. Ondansetron has been proved to be valid in preventing postanaesthesia shivering (PAS) in several studies. However, its efficiency and safety are still disputable. We therefore performed an updated meta-analysis of randomised controlled trials (RCTs) for evaluation and to clarify this issue. Methods A literature search using the PubMed, Embase™ and Cochrane Library databases was… 
Comparison of Ondansetron & Dexmedetomidine for Prevention of Post Spinal Shivering
ABSTRACT: INTRODUCTION: Spinal Anaesthesia is a major component of Anaesthetist's tool set and is widely used in Anaesthesia practices. A frequent problem encountered after spinal Anaesthesia is
Comparison of High Dose Ondansetron versus Low Dose Ondansetron for Prevention from Postansthesia Shivering
TLDR
Ondansetron use regardless of the dose was superior to placebo in terms of PAS intensity and nausea and vomiting prevention and meperidine requirement for shivering control.
Ondansetron VS Pethidine for The Prevention of Postoperative Shivering
TLDR
Ondansetron is effective as Pethidine for prevention of postoperative shivering, however, side effects postoperative nausea & vomiting were significantly higher in pethidine group.
Postanaesthetic shivering – from pathophysiology to prevention
TLDR
Control of PS is possible and clinically effective with simple pharmacological interventions combined with non pharmacological methods, but to be consistent with the most up-to-date, evidence-based practice, future antishivering treatment protocols should optimize methodological rigor and transparency.
Postanaesthetic shivering - from pathophysiology to prevention.
  • M. B. López
  • Medicine
    Romanian journal of anaesthesia and intensive care
  • 2018
TLDR
Control of PS is possible and clinically effective with simple pharmacological interventions combined with non pharmacological methods, but to be consistent with the most up-to-date, evidence-based practice, future antishivering treatment protocols should optimize methodological rigor and transparency.
Cross-sectional Study on Effects of Ondansetron and Meperidine in the Prevention of Postoperative Shivering after Spinal Anesthesia
TLDR
8mg ondansetron and 0.4 mg/kg of meperidine are equally effective in managing postoperative shivering; however, ondANSetron has an additional effect of reducing the incidence of postoperative nausea among patients undergoing caesarean section with spinal anesthesia.
Treatment of postoperative shivering after laparoscopic cholecystectomy under general anesthesia: a comparative clinical study
TLDR
Ondansetron seems to be the drug to least affect hemodynamics, with less adverse effects than ketamine in comparison with pethidine, and effectively managed postoperative shivering with decreased incidence of recurrence of shivering.
Comparative Study of the Prophylactic Effects of Intravenous Injection of Dexmedetomidine, Ondansetron, and Pethidine on Postoperative Shivering of Abdominal Surgery under General Anesthesia: A Randomized Clinical Trial
TLDR
The use of all three drugs of dexmedetomidine, ondansetron, and pethidine is effective in decreasing the incidence of postoperative shivering, but the use of Dexmedetamidine is associated with less postoperativeShivering, better hemodynamic stability, and fewer other postoperative complications.
Comparison of weight-adjusted dose versus fixed dose ondansetron in preventing shivering following spinal anaesthesia for caesarean deliveries
TLDR
Ondansetron weight adjusted dose at 0.1mg/kg, reduced the severity of shivering when compared to a fixed dose ondANSetron at 4mg, which was found to be an effective treatment and prevention of post-spinal anesthesia shivering.
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