Efficacy response of inhaled beclomethasone dipropionate in asthma is proportional to dose and is improved by formulation with a new propellant.

@article{Busse1999EfficacyRO,
  title={Efficacy response of inhaled beclomethasone dipropionate in asthma is proportional to dose and is improved by formulation with a new propellant.},
  author={William W. Busse and Shari A Brazinsky and Kalen Jacobson and Wes Stricker and K Schmitt and J A Vanden Burgt and Deborah Donnell and Scott Hannon and Gene L. Colice},
  journal={The Journal of allergy and clinical immunology},
  year={1999},
  volume={104 6},
  pages={1215-22}
}
BACKGROUND This study tested the hypothesis that there would be improved asthma control with increasing doses of beclomethasone dipropionate (BDP) formulated in hydrofluoroalkane-134a (HFA-BDP) and the standard chlorofluorocarbon propellants (CFC-BDP). Because HFA-BDP has improved lung deposition compared with CFC-BDP, this study also tested the hypothesis that HFA-BDP would provide more effective control of asthma than CFC-BDP. METHODS In this multicenter, randomized, parallel-group blinded… CONTINUE READING

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