Efficacy profiles of daptomycin for treatment of invasive and noninvasive pulmonary infections with Streptococcus pneumoniae.

Abstract

Daptomycin is a novel lipopeptide antibiotic with excellent activity against Gram-positive bacterial pathogens, but its therapeutic value for the treatment of invasive pneumococcal disease compared to that for the treatment of pneumococcal pneumonia is incompletely defined. We investigated the efficacy of daptomycin in two models of Streptococcus pneumoniae… (More)
DOI: 10.1128/AAC.00943-09

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@article{Henken2010EfficacyPO, title={Efficacy profiles of daptomycin for treatment of invasive and noninvasive pulmonary infections with Streptococcus pneumoniae.}, author={Stefanie Henken and Jennifer Bohling and Jens Martens-Lobenhoffer and James C. Paton and Abiodun Ogunniyi and David E. Briles and Vyvyan C. Salisbury and Dirk Wedekind and Stefanie Margarethe Bode-B{\"o}ger and Thomas Welsh and Franz Christoph Bange and Tobias Welte and Ulrich A. Maus}, journal={Antimicrobial agents and chemotherapy}, year={2010}, volume={54 2}, pages={707-17} }