Efficacy of virosome hepatitis A vaccine in young children in Nicaragua: randomized placebo-controlled trial.

@article{Prez2003EfficacyOV,
  title={Efficacy of virosome hepatitis A vaccine in young children in Nicaragua: randomized placebo-controlled trial.},
  author={Orlando Mayorga P{\'e}rez and Christian Herzog and Martina Zellmeyer and Arnoldo Lo{\'a}isiga and G. G. Fr{\"o}sner and Matthias Egger},
  journal={The Journal of infectious diseases},
  year={2003},
  volume={188 5},
  pages={671-7}
}
Immunization of young children could control hepatitis A virus (HAV) infection, but the efficacy of hepatitis A vaccines in early childhood is unknown. In a randomized, double-blind trial of a single dose of a virosome-formulated, aluminum-free inactivated HAV vaccine in Nicaragua, 274 children (age range, 1.5-6 years) received vaccine or placebo injections; 239 children seronegative for hepatitis A were included in the primary efficacy analysis. HAV infection documented by immunoglobulin M… CONTINUE READING

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Single-dose administration of inactivated hepatitis A vaccination in the context of hepatitis A vaccine recommendations.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases • 2013

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