Efficacy of vaccination with porcine reproductive and respiratory syndrome virus following challenges with field isolates in Japan.

@article{Okuda2008EfficacyOV,
  title={Efficacy of vaccination with porcine reproductive and respiratory syndrome virus following challenges with field isolates in Japan.},
  author={Yo Okuda and Maho Kuroda and Masaaki Ono and Sumiko Chikata and Isao Shibata},
  journal={The Journal of veterinary medical science},
  year={2008},
  volume={70 10},
  pages={1017-25}
}
The objective of this study was to evaluate the influences of genetic and antigenic variations in field isolates of porcine reproductive and respiratory syndrome virus (PRRSV) on vaccine efficacy. Four-week-old pigs were vaccinated with a commercial modified live virus vaccine. Four weeks after vaccination, pigs in both the vaccinated group and the non-vaccinated group were challenged intranasally with 10(7) TCID(50) of PRRSV wt-11 (Experiment 1) or PRRSV wt-7 (Experiment 2). Based on genome… CONTINUE READING
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