Efficacy of topical tacrolimus for treating the malar rash of systemic lupus erythematosus.

@article{Kanekura2003EfficacyOT,
  title={Efficacy of topical tacrolimus for treating the malar rash of systemic lupus erythematosus.},
  author={Takuro Kanekura and Noriko Yoshii and Kenjiro Terasaki and Hayao Miyoshi and Tamotsu Kanzaki},
  journal={The British journal of dermatology},
  year={2003},
  volume={148 2},
  pages={353-6}
}
The rash of systemic lupus erythematosus (SLE) is usually treated with topical corticosteroids, but prolonged use causes adverse cutaneous side-effects. We assessed the efficacy of topical tacrolimus for treating the skin lesions of SLE. Three patients with SLE affecting their facial skin applied 0.1% tacrolimus ointment on one side of their face twice daily for 3 weeks, in conjunction with a sunscreen cream. After 3 weeks, erythema on the treated side was ameliorated in all three patients… CONTINUE READING
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