Efficacy of topical phenol decontamination strategies on severity of acute phenol chemical burns and dermal absorption: in vitro and in vivo studies in pig skin

@article{MonteiroRiviere2001EfficacyOT,
  title={Efficacy of topical phenol decontamination strategies on severity of acute phenol chemical burns and dermal absorption: in vitro and in vivo studies in pig skin},
  author={Nancy A Monteiro-Riviere and Alfred O. Inman and Hilary A. Jackson and Brendan J. Dunn and Stephen S. Dimond},
  journal={Toxicology and Industrial Health},
  year={2001},
  volume={17},
  pages={104 - 95}
}
Pure phenol is colorless and used in the manufacture of phenolic resins, plastics, explosives, fertilizers, paints, rubber, textiles, adhesives, pharmaceuticals, paper, soap, and wood preservatives. The purpose of this study was to compare the efficacy of several phenol decontamination strategies following dermal exposure using the pig as a model for human exposure, and then assess the effect of the two best treatments on phenol absorption in the isolated perfused porcine skin flap (IPPSF). Six… 
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