Efficacy of the potentized homeopathic drug, Carcinosin 200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-dimethylaminoazobenzene-induced hepatocarcinogenesis in mice.

@article{Biswas2005EfficacyOT,
  title={Efficacy of the potentized homeopathic drug, Carcinosin 200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-dimethylaminoazobenzene-induced hepatocarcinogenesis in mice.},
  author={Surjyo Jyoti Biswas and Surajit Pathak and Nandini Bhattacharjee and Jayanta Kumar Das and Anisur Rahman Khuda-Bukhsh},
  journal={Journal of alternative and complementary medicine},
  year={2005},
  volume={11 5},
  pages={
          839-54
        }
}
OBJECTIVES This study was conducted to examine whether the potentized homeopathic remedy Carcinosin 200, fed alone and in combination with Chelidonium 200, has differential protective effects against p-dimethylaminoazobenzene (p-DAB)-induced hepatocarcinogenesis in mice. DESIGN Liver tumors were induced in mice through chronic feeding of p-DAB (initiator) and phenobarbital (PB, promoter). The mice were divided into two subgroups: (1) one was fed potentized Alcohol 200 and served as controls… 
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34 Citations

Amelioration of Carcinogen-Induced Toxicity in Mice by Administration of a Potentized Homeopathic Drug, Natrum Sulphuricum 200

Administration of Nat Sulph 200 reduced genomic damage, activities of AcP, AlkP, AST, ALT, LPO and increased GSH content, and less number of liver tumors were observed in Gr.

Protective potentials of a potentized homeopathic drug, Lycopodium-30, in ameliorating azo dye induced hepatocarcinogenesis in mice

Both the assay systems indicated considerable protective potentials of the homeopathic remedy against p-DAB induced hepatocarcinogenesis in mice.

Efficacy of a plant extract (Chelidonium majus L.) in combating induced hepatocarcinogenesis in mice.

A potentized homeopathic drug, Arsenicum Album 200, can ameliorate genotoxicity induced by repeated injections of arsenic trioxide in mice.

Compared with controls, the drug fed mice showed reduced toxicity at statistically significant levels in respect of all the parameters studied, thereby indicating protective potentials of the homeopathic drug against chronic arsenic poisoning.

Supportive Evidence for the Anticancerous Potential of Alternative Medicine against Hepatocarcinogenesis in Mice

Lyco-200 reduced cytogenetic damages yielding positive modulations of all biochemical, pathological and other risk factors, cell viability and expression of p53 protein and matrix metalloproteinases as compared to controls.

Effect of Chelidonium majus on Metabolic Abnormalities Induced by HAART in Mice

The effect of Chelidonium majus on metabolic alterations induced in mice subjected to HAART was evaluated and it was found that the drug had an anti-tumor and anti-genotoxic effect.

Effect of ultra-diluted nux vomica and cyclophosphamide solutions on the genotoxicity of allopathic cyclophosphamid

The dynamized ultra-diluted nux vomica and CF compounds showed lower white cell counts in mice and were able to mitigate the effect of CF on thymic cortical reduction in mice, but no compound was able to mitigating the genotoxic effects of CF in micronucleus assay.

Induction of Apoptosis of Tumor Cells by Some Potentiated Homeopathic Drugs

The data indicate that apoptosis is one of the mechanisms of tumor reduction of homeopathic drugs, and a comparison of potentiated drugs with their mother tincture indicated that the potentiate drugs have biological activity similar to that of their motherTincture in spite of ultradilution.

Effect of homeopathic medicines on transplanted tumors in mice.

The findings support that homeopathic preparations of Ruta and Hydrastis have significant antitumour activity and the mechanism of action of these medicines is not known at present.

Anti-proliferative effects of homeopathic medicines on human kidney, colon and breast cancer cells

References

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The homeopathic drug Chelidonium exhibited anti-tumor and anti-genotoxic activities and also favorably modulated activities of some marker enzymes in mice compared to suitable controls.

Evaluation of protective potentials of a potentized homeopathic drug, Chelidonium majus, during azo dye induced hepatocarcinogenesis in mice.

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