Efficacy of the oral fluorouracil pro-drug capecitabine in cancer treatment: a review.

@article{Koukourakis2008EfficacyOT,
  title={Efficacy of the oral fluorouracil pro-drug capecitabine in cancer treatment: a review.},
  author={Georgios V Koukourakis and Vassilis Kouloulias and Michael J Koukourakis and Georgios A Zacharias and Haralabos Zabatis and John Kouvaris},
  journal={Molecules},
  year={2008},
  volume={13 8},
  pages={1897-922}
}
Capecitabine (Xeloda) was developed as a pro-drug of fluorouracil (FU), with the aim of improving tolerability and intratumor drug concentrations through its tumorspecific conversion to the active drug. The purpose of this paper is to review the available information on capecitabine, focusing on its clinical effectiveness against various carcinomas… CONTINUE READING