Efficacy of the Mirasol pathogen reduction technology system against severe fever with thrombocytopenia syndrome virus (SFTSV).

Abstract

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tickborne virus in the Bunyaviridae family. This virus has recently been found in China, Japan and Korea. The risk of transfusion-transmitted SFTSV infection (TTI-SFTSV) is a concern because person-to-person transmission resulting from contact with SFTSV-contaminated blood has been reported. Therefore, we investigated the efficacy of the Mirasol pathogen reduction technology (PRT) system for inactivating SFTSV in vitro. The Mirasol PRT system achieved a > 4.11 log10 reduction value (LRV) for SFTSV. In conclusion, we showed that the Mirasol PRT system could potentially be used to reduce the risk of TTI-SFTSV.

DOI: 10.1111/vox.12305

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Cite this paper

@article{Shinohara2015EfficacyOT, title={Efficacy of the Mirasol pathogen reduction technology system against severe fever with thrombocytopenia syndrome virus (SFTSV).}, author={Naoya Shinohara and Chieko Matsumoto and Masashi Chatani and Shin-ichi Uchida and Tetsushi Yoshikawa and Masayuki Shimojima and Masahiro Satake and Kenji Tadokoro}, journal={Vox sanguinis}, year={2015}, volume={109 4}, pages={417-9} }