Efficacy of thalidomide on trinitrobenzene sulfonate-induced colitis in young rats and its mechanism.


BACKGROUND Thalidomide could relieve clinical symptoms and intestinal mucosal lesions effectively in children with refractory inflammatory bowel disease (IBD) from the pre-clinical study. This study aimed to observe the therapeutic effect of thalidomide by the established animal model of IBD model of 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced… (More)


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