Efficacy of thalidomide on trinitrobenzene sulfonate-induced colitis in young rats and its mechanism.

Abstract

BACKGROUND Thalidomide could relieve clinical symptoms and intestinal mucosal lesions effectively in children with refractory inflammatory bowel disease (IBD) from the pre-clinical study. This study aimed to observe the therapeutic effect of thalidomide by the established animal model of IBD model of 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced… (More)

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