Efficacy of sulfadoxine-pyrimethamine for prevention of placental malaria in an area of Kenya with a high prevalence of malaria and human immunodeficiency virus infection.

@article{Parise1998EfficacyOS,
  title={Efficacy of sulfadoxine-pyrimethamine for prevention of placental malaria in an area of Kenya with a high prevalence of malaria and human immunodeficiency virus infection.},
  author={M. Parise and J. Ayisi and B. Nahlen and L. J. Schultz and J. Roberts and A. Misore and R. Muga and A. Oloo and R. Steketee},
  journal={The American journal of tropical medicine and hygiene},
  year={1998},
  volume={59 5},
  pages={
          813-22
        }
}
A fever case management (CM) approach using sulfadoxine-pyrimethamine (SP) was compared with two presumptive intertmittent SP treatment regimens in the second and third trimesters in pregnant primigravidae and secundigravidae in an area of intense Plasmodium falciparum malaria transmission in western Kenya. [...] Key Method The investigation evaluated efficacy of the antimalarial regimens for prevention of placental malaria and examined the effect of human immunodeficiency virus (HIV) infection on antimalarial…Expand
400 Citations

Paper Mentions

Interventional Clinical Trial
The purpose of this study is to determine whether repeated courses of sulphadoxine-pyrimethamine (SP) in combination with azithromycin given at Antenatal Clinic, leads to lower… Expand
ConditionsAnaemia, Malaria in Pregnancy, Sexually Transmitted Infections
InterventionDrug
Interventional Clinical Trial
In Malawi, the standard of care to prevent malaria during pregnancy at the time of the study was a two dose sulfadoxine-pyrimethamine intermittent protective treatment (SP IPT) regimen… Expand
ConditionsHIV Infections, Malaria, Falciparum
InterventionDrug
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