Efficacy of steroid withdrawal and low-dose interferon treatment in chronic active hepatitis B. Results of a randomized multicenter trial. Swiss Association for the Study of the Liver.

@article{Reichen1994EfficacyOS,
  title={Efficacy of steroid withdrawal and low-dose interferon treatment in chronic active hepatitis B. Results of a randomized multicenter trial. Swiss Association for the Study of the Liver.},
  author={Juerg Reichen and Leonardo Bianchi and Philippe C. Frei and Pierre Jean Mal{\'e} and Daniel Lavanchy and Martin S Schmid},
  journal={Journal of hepatology},
  year={1994},
  volume={20 2},
  pages={168-74}
}
Fifty-six patients with biopsy-proven, chronic active hepatitis B were included in a multi-center, randomized trial comparing steroid withdrawal followed by 1.5 MU recombinant interferon alpha 2b (Intron) with placebo withdrawal followed by either 1.5 or 5 MU interferon. The patients were equally distributed between the treatment groups with respect to biochemical and histologic activity as well as with respect to DNA levels and quantitative liver function tests. One patient was lost to follow… CONTINUE READING

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