Efficacy of single-bolus administration of sodium bicarbonate to prevent contrast-induced nephropathy in patients with mild renal insufficiency undergoing an elective coronary procedure.

@article{Tamura2009EfficacyOS,
  title={Efficacy of single-bolus administration of sodium bicarbonate to prevent contrast-induced nephropathy in patients with mild renal insufficiency undergoing an elective coronary procedure.},
  author={Akira Tamura and Yukie Goto and Kumie Miyamoto and Shigeru Naono and Yoshiyuki Kawano and Munenori Kotoku and Toru Watanabe and Jun-ichi Kadota},
  journal={The American journal of cardiology},
  year={2009},
  volume={104 7},
  pages={921-5}
}
We sought to clarify whether a single-bolus intravenous administration of sodium bicarbonate in addition to hydration with sodium chloride prevents contrast-induced nephropathy (CIN). One hundred forty-four patients with mild renal insufficiency (serum creatinine >1.1 to <2.0 mg/dl) undergoing an elective coronary procedure were randomly assigned to the following 2 groups: standard hydration with sodium chloride plus single-bolus intravenous administration of sodium bicarbonate (20 mEq… CONTINUE READING
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