Efficacy of recombinant interferon-alpha (rIFN-alpha) in polycythaemia vera: a study of 17 patients and an analysis of published data.

@article{Taylor1996EfficacyOR,
  title={Efficacy of recombinant interferon-alpha (rIFN-alpha) in polycythaemia vera: a study of 17 patients and an analysis of published data.},
  author={Paul Canaday Taylor and Gerard Dolan and Jack Pei Sheng. Ng and Beverley Paul and Rod Collin and John Thomas Reilly},
  journal={British journal of haematology},
  year={1996},
  volume={92 1},
  pages={
          55-9
        }
}
The efficacy and tolerability of rIFN-alpha has been evaluated in 17 selected patients with symptomatic polycythaemia vera, diagnosed according to the PRV Study Group criteria. Complete disease control (CR) was achieved, after 1-12 months, in nine patients, with partial control in a further five cases. Three patients failed to respond. Pruritus significantly improved in 83% (10/12) of cases, following 1-28 weeks of treatment. Six patients (35%), however, were unable to tolerate rIFN-alpha, on… CONTINUE READING
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