Efficacy of pneumococcal vaccination in adults: a meta-analysis.

  title={Efficacy of pneumococcal vaccination in adults: a meta-analysis.},
  author={Anke Huss and Pippa Scott and Andreas E. Stuck and Caroline Trotter and Matthias Egger},
  journal={Archives of internal medicine},
  volume={154 23},
BACKGROUND Clinical trials and meta-analyses have produced conflicting results of the efficacy of unconjugated pneumococcal polysaccharide vaccine in adults. We sought to evaluate the vaccine's efficacy on clinical outcomes as well as the methodologic quality of the trials. METHODS We searched several databases and all bibliographies of reviews and meta… CONTINUE READING