Efficacy of plasma therapy in atypical hemolytic uremic syndrome with complement factor H mutations

@article{Lapeyraque2008EfficacyOP,
  title={Efficacy of plasma therapy in atypical hemolytic uremic syndrome with complement factor H mutations},
  author={Anne-Laure Lapeyraque and Eric Wagner and V{\'e}ronique Phan and M Clermont and A{\"i}cha M{\'e}rouani and V{\'e}ronique Fr{\'e}meaux-Bacchi and Timothy H. J. Goodship and Pierre Robitaille},
  journal={Pediatric Nephrology},
  year={2008},
  volume={23},
  pages={1363-1366}
}
Atypical hemolytic uremic syndrome (aHUS) frequently results in end-stage renal failure and can be lethal. Several studies have established an association between quantitative or qualitative abnormalities in complement factor H and aHUS. Although plasma infusion and exchange are often advocated, guidelines have yet to be established. Long-term outcome for patients under treatment is still unknown. We describe a patient who, at 7 months of age, presented with aHUS associated with combined de… CONTINUE READING

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