Efficacy of photodynamic therapy in vulvar lichen sclerosus treatment based on immunohistochemical analysis of CD34, CD44, myelin basic protein, and Ki67 antibodies.

@article{Olejek2010EfficacyOP,
  title={Efficacy of photodynamic therapy in vulvar lichen sclerosus treatment based on immunohistochemical analysis of CD34, CD44, myelin basic protein, and Ki67 antibodies.},
  author={Anita Olejek and Katarzyna Stęplewska and Andrzej Gabriel and Iwona Kozak-Darmas and Anna Jarek and Sylwia Kellas-Ślęczka and Filip Bydliński and Karolina Sieroń-Stołtny and Stanisław Hor{\'a}k and Artur Chełmicki and Aleksander L Sieron},
  journal={International journal of gynecological cancer : official journal of the International Gynecological Cancer Society},
  year={2010},
  volume={20 5},
  pages={879-87}
}
INTRODUCTION Lichen sclerosus (LS) is a chronic skin and mucosa inflammatory disease. It affects mainly the female anogenital area especially in postmenopausal period. The main symptoms include pruritus, burning, pain, sometimes urinary problems, or difficulties in defecation. Usually, porcelain-white plaques are seen in the skin and mucosa. The etiology and pathogenesis of LS are still uncertain. There are some research studies on possible genetic predisposition, yet autoimmune, hormonal, or… CONTINUE READING